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Updated: Jul 20, 2025

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SARS-CoV-2的ORF3a蛋白的整个序列同质模型的结构和动态:微秒分子动态模拟的洞察力

Shaila Akter1, Md Jahirul Islam1, Md Ackas Ali2

  • 1Division of Infectious Diseases and Division of Computer-Aided Drug Design, The Red-Green Research Centre, BICCB, Tejgaon, Dhaka, Bangladesh.

Journal of biomolecular structure & dynamics
|August 2, 2023
PubMed
概括

这项研究将SARS-CoV-2ORF3a蛋白质的全序列同质模型与其冷EM结构进行比较. 同源模型显示出更稳定的动态和相互作用,有助于理解病毒的病变发生.

关键词:
在ORF3a中,ORF3a是指ORF3a.这就是SARS-CoV-2病毒.自由能源的景观.同源性建模的同源性建模分子对接的分子对接.分子动力学模拟模拟引导了分子动力学.

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