Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

148
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
148
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

1.0K
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
1.0K
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

2.8K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
2.8K
Ethical Dilemmas II01:30

Ethical Dilemmas II

1.1K
Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
1.1K
Pharmacovigilance01:19

Pharmacovigilance

891
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
891
Ethical Issues01:27

Ethical Issues

1.0K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
1.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The Secretome of a Cachexia-Inducing Lung Tumor Impairs Mitochondrial Function and Skeletal Muscle Differentiation.

Cancers·2026
Same author

Filling the mechanistic and methodological gaps for predicting cytokine release syndrome in humans.

Frontiers in pharmacology·2026
Same author

Accelerating AOP Development in the AOP-Wiki with AI: A Practical Road Map for the Community.

Environmental science & technology·2026
Same author

Methods2AOP: A Collaboration to Strengthen the Integration of Test Methods into the Adverse Outcome Pathway Framework.

F1000Research·2026
Same author

Best Practices for the Development and Application of Bioinformatics Approaches for Species Extrapolation in Chemical Safety Assessment.

Integrated environmental assessment and management·2026
Same author

Atypical Ductular Reactions Are a Distinct Regenerative Phenomenon in Patients With Hepatocellular Carcinoma (HCC) After Transarterial Chemoembolization.

Laboratory investigation; a journal of technical methods and pathology·2026

相关实验视频

Updated: Jul 20, 2025

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

23.7K

为什么不良结果的途径需要公平.

Clemens Wittwehr1, Laure-Alix Clerbaux1, Stephen Edwards2

  • 1European Commission, Joint Research Centre (JRC), Ispra, Italy.

ALTEX
|August 2, 2023
PubMed
概括

不良结果途径 (AOP) 对于化学品风险评估和减少动物试验至关重要. 使用FAIR原则使AOP能够在机器上操作,提高了它们的可见性,信任性和可重复使用性,以获得更好的科学影响.

关键词:
公平的数据是公平的.负面结果途径 (AOPs) 是指负面结果的途径.机器可操作性 机器可操作性在信任信任信任信任信任信任.可见性可见性可见性

更多相关视频

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

11.9K
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.5K

相关实验视频

Last Updated: Jul 20, 2025

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

23.7K
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

11.9K
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.5K

科学领域:

  • 毒理学和风险评估
  • 计算毒理学计算毒理学
  • 环境科学 环境科学

背景情况:

  • 不良结果途径 (AOPs) 正在获得化学风险和因果关系评估的引力.
  • AOP对于推进化学安全评估和减少对动物试验的依赖至关重要.
  • 由于它们缺乏机器可操作性,AOPs的全部潜力受到限制.

研究的目的:

  • 要突出机器可操作的不利结果途径 (AOP) 的必要性.
  • 解释FAIR原则 (可查找性,可访问性,互操作性,可重复使用性) 如何支持AOP机器可操作性.
  • 讨论 FAIRifying AOPs 的好处,包括提高可见性和可信度.

主要方法:

  • 文学综述和对AOP和FAIR原则的概念分析.
  • 讨论AOP数据利用当前的挑战.
  • 详细阐述了FAIR数据原则对AOP知识的应用.

主要成果:

  • AOPs需要机器可操作性,以最大限度地影响风险评估.
  • 公平原则对于实现AOP机器可操作性至关重要.
  • 对AOP的公平化导致数据可见性提高和科学信任增加.

结论:

  • 负面结果途径 (AOP) 必须是公平的,才能充分利用.
  • 在AOP中实施FAIR原则是推进化学风险评估的关键.
  • 公平的数据实践将提高毒理学知识的可靠性和可访问性.