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在缺血性中风中,紧急医疗服务的血液采集是否缩短了组织等离子素激活器的时间?
Abigail L Hulsizer1, Sondra Davis2, Caitlin M Gibson3
1College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA.
概括
实施急性缺血性中风患者的急诊医疗服务 (EMS) 的医院前血液抽取并没有显著减少门到针的时间. 这一策略并没有改善对关键的纤维溶解药物治疗的及时管理.
科学领域:
- 神经学 神经学
- 紧急医疗 紧急医疗
- 医疗保健服务研究 医疗服务研究
背景情况:
- 缺血性中风是美国长期残疾的主要原因.
- 及时的纤维解药治疗对于减少中风相关残疾至关重要.
- 积极寻求减少治疗延迟的策略.
研究的目的:
- 评估急诊医疗服务 (EMS) 的医院前实验室血液抽取是否可以减少急性缺血性中风患者的门到针时间.
- 为了比较由EMS抽取血液的患者与在医院抽取血液的患者之间的门到针时间.
主要方法:
- 一项回顾性,单中心的队列研究分析了2015-2017年的数据.
- 包括被诊断患有急性缺血性中风的成年患者,他们接受了alteplas.
- 在EMS血液抽取和通常护理的患者之间比较了门到针的时间.
主要成果:
- 该研究包括66名患者:EMS组28名,常规护理组38名.
- 门到针的中位时间为EMS组的57.5分钟,通常护理组的55.0分钟 (p=0.818).
- 没有观察到门到针时间的统计学上显著差异.
结论:
- 在急性缺血性中风患者的EMS人员在医院前收集血液并没有显著缩短门到针的时间.
- 目前的医院前血液采集协议并不能加速纤维溶解药物治疗的开始.
- 可能需要进一步的研究来优化医院前中风治疗途径.
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