基于天然生物聚合物的药物输送系统的最新发展
Tanzeela Fazal1, Bibi Nazia Murtaza2, Mazloom Shah3
1Department of Chemistry, Abbottabad University of Science and Technology Pakistan tanzeelafazal@yahoo.com.
RSC advances
|August 2, 2023
概括
生物聚合物为先进的药物输送系统 (DDS) 提供了一个有希望的途径. 这些天然材料使得药物可以被向地输送,提高治疗效果,同时最大限度地减少副作用,从而改善患者的治疗结果.
科学领域:
- 生物材料科学 生物材料科学
- 制药科学 制药科学
- 纳米技术纳米技术
背景情况:
- 针对性地将药物输送到患病部位仍然是医学的重大挑战.
- 目前的药物输送系统 (DDS) 经常在有效性和系统性毒性方面扎.
- 生物聚合物正在成为创新DDS的先进材料.
研究的目的:
- 审查基于生物聚合物的药物递送系统 (DDS) 的最新进展.
- 探索这些新型DDS的潜在临床应用.
- 总结生物聚合物DDS的合成技术和配方策略.
主要方法:
- 对DDS.生物聚合物应用的当前文献的综述.
- 分析各种生物聚合物,包括纤维素,酸盐,粉和蛋白质.
- 讨论用于DDS制造和配方的合成技术.
主要成果:
- 生物聚合物表现出理想的特性,如生物降解性,生物相容性和高药物载荷能力.
- 基于生物聚合物的DDS在眼睛,牙,皮肤和鼻腔内输送方面显示出潜力.
- 各种合成方法可以创建定制的生物聚合物DDS配方.
结论:
- 基于生物聚合物的DDS代表了针对性治疗策略的重大进步.
- 与传统方法相比,这些系统提供了更高的疗效和更低的毒性.
- 进一步的开发有望对临床转化和创新的药物配方产生影响.
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