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Updated: Jul 20, 2025

Rapid Generation of Amyloid from Native Proteins In vitro
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对拥挤条件的反应揭示了折叠蛋白质的粉样蛋白形成的紧核

Tony E R Werner1, Istvan Horvath1, Pernilla Wittung-Stafshede1

  • 1Department of Biology and Biological Engineering, Chalmers University of Technology, S-41296 Gothenburg, Sweden.

QRB discovery
|August 2, 2023
PubMed
概括

细胞拥挤通过促进核化而不是展开来加速鱼蛋白粉样蛋白的形成. 这与其他amyloidogenic蛋白质形成鲜明对比,突出显示了细胞环境对蛋白质错折的独特影响.

关键词:
粉样蛋白的形成大分子分子拥挤.氧化氧化氧化物是如何形成的蛋白质聚合蛋白质的聚合物这是一种β-parvalbumin.

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