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儿童和婴儿持续流动全人工心脏的人体安装:视觉和虚拟评估
Chihiro Miyagi1, Munir Ahmad2, Jamshid H Karimov1,3
1Department of Biomedical Engineering, Cleveland Clinic Lerner Research Institute, Cleveland, OH, United States.
Frontiers in cardiovascular medicine
|August 2, 2023
概括
这项研究评估了针对儿科和婴儿先天性心脏手术患者的连续流量全人工心脏 (CFTAH). 婴儿CFTAH适合所有患者,而儿科CFTAH适合52.5%,确定了关键的适合参数.
科学领域:
- 生物医学工程 生物医学工程
- 儿童心脏病学 儿童心脏病学
- 胸部外科手术 胸部外科手术
背景情况:
- 在儿科患者中,先天性心脏病需要先进的循环支持.
- 目前正在为儿科和婴儿群体开发小型连续流动全人工心脏 (CFTAH).
- 评估设备的合适性对于人工心脏植入的有效性至关重要.
研究的目的:
- 为了确定儿科 (P-CFTAH) 和婴儿 (I-CFTAH) 连续流量整体人工心脏的解剖学和虚拟适应.
- 确定影响先天性心脏手术患者P-CFTAH适合性的关键患者参数.
- 评估CFTAHs对于小患者群体的可行性.
主要方法:
- 利用P-CFTAH和I-CFTAH的3D打印模型对40名儿科心脏手术患者进行虚拟安装.
- 分析了三个婴儿 (4.2,5.3,10.2公斤) 的手术前胸部放射和计算机断层扫描 (CT) 影像数据.
- 确定P-CFTAH适合的体重,身高和身体表面积的临界界值.
主要成果:
- 在I-CFTAH中,所有33名被评估的患者都表现出合适的适应性.
- 在40名患者中,P-CFTAH适合21名患者 (52.5%),其中19名患者 (47.5%) 显示不适合.
- 影响P-CFTAH适合的显著尺寸变化 (p < 0.0001) 包括体重 (<5.71 kg),身高 (<59.0 cm) 和身体表面积 (<0.31 m2).
结论:
- 在先天性心脏病患者中确定了P-CFTAH和I-CFTAH的适当适应范围.
- 这项研究表明,对于小患者群体,儿科和婴儿CFTAH设备的可行性.
- 确定了对于成功植入P-CFTAH至关重要的特定人体测量标准.
相关概念视频
01:20Assessment of Ventilation I: Respiratory Rate
Assessment of Ventilation
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
01:29Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory Depth
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
01:25Assessment of the Cardiovascular System IV: Auscultation
Cardiac auscultation is a clinical skill used to assess heart function and detect abnormalities. It involves listening to heart sounds at specific anatomical locations through a stethoscope.
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.