使用多电解质稳定纳米脂质体对益生菌进行封装,以在恶劣条件下提高生存能力
Muhammad Adeel1, Muhammad Afzaal1, Farhan Saeed1
1Food Safety and Biotechnology Laboratory, Department of Food Science, Government College University, Faisalabad, Pakistan.
Journal of food science
|August 2, 2023
概括
新的凝 - 基托涂层纳米脂质体有效地保护乳酸菌酸性菌的益生菌. 这项创新提高了食品中的益生菌生存能力,解决了改善功能性食品的关键行业挑战.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物技术是生物技术.
- 材料科学 材料科学 材料科学
背景情况:
- 益生菌的生存能力和稳定性是食品行业面临的关键挑战.
- 乳杆菌酸性是一种常用的益生菌,在食品矩阵中稳定性有限.
研究的目的:
- 开发和表征凝-基托 (GE-CH) 聚电解质涂层纳米脂质体,以增强益生菌的传递.
- 为了评估纳米载体系统内封装的Lactobacillus acidophilus的稳定性和活力.
主要方法:
- 纳米脂质体被配制并涂上GE-CH多电解质.
- 分析了粒子大小,泽塔潜力,表面形态 (SEM) 和化学结构 (FTIR).
- 在模拟的胃肠道条件下评估了封装效率和生存能力.
- 使用X射线衍射研究了结晶性.
主要成果:
- 用GE-CH涂层的纳米脂质体呈现的粒子大小在131.7-431.6nm之间,泽塔电位在-42.2到-9.1mV之间.
- SEM证实了具有光滑表面的球形纳米脂质体,FTIR证实了成功的GE-CH涂层和益生菌封装.
- X射线衍射表明半晶性质受到GE-CH涂层的影响.
- 封装的益生菌在模拟的胃肠道环境中显著改善了生存能力.
结论:
- GE-CH 聚电解质涂层有效地稳定了纳米脂质体,并保护了封装的 Lactobacillus acidophilus.
- 这种纳米载体系统为功能性食品中提供益生菌提供了一个有希望的解决方案.
- 开发的技术可以提高益生菌在食品加工应用中的稳定性和有效性.
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