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对基底细胞癌的成本意识治疗的建议
Palak V Patel1, Jessica N Pixley2, Hannah S Dibble2
1Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, 4618 Country Club Road, Winston-Salem, NC, 27104, USA. palpatel@wakehealth.edu.
Dermatology and therapy
|August 2, 2023
概括
基底细胞癌 (BCC) 的成本效益高的治疗方法优先考虑表面BCC的切和电解脱 (C&E) 或冷手术,以及状BCC的C&E,冷手术或5-fluorouracil (5-FU). 建议对巨型BCC进行放射治疗.
科学领域:
- 皮肤病学 皮肤病学
- 卫生经济学 卫生经济学
背景情况:
- 基底细胞癌 (BCC) 是一种常见的皮肤癌,每年影响数百万人.
- 对BCC的治疗费用对患者和医疗保健系统来说可能是一个巨大的财务负担.
- 成本效益是选择BCC管理策略的关键因素.
研究的目的:
- 开发一种以降低成本为重点的方法来管理基底细胞癌.
- 为了确定各种BCC类型和大小的最经济的治疗选择.
主要方法:
- 使用PubMed.进行了关于BCC治疗有效性的综合文献搜索.
- 治疗费用从医疗保险国家费用表,GoodRx和制药公司收集.
- 根据美国皮肤病学会 (AAD) 的指导方针制定了成本有效的BCC治疗建议.
主要成果:
- 对于表面性BCC (<0.5厘米),切割和电解剖 (C&E) 和冷手术是最便宜的选择 ($143).
- 对于结节性BCC (1.1-2厘米),C&E,冷手术和5-甲 (5-FU) 提供了具有成本效益的治疗 (183美元至186美元).
- 治疗费用差异很大,像vismodegib和sonidegib这样的先进疗法在巨型BCC中超过139,000美元.
结论:
- 一个具有成本意识的算法推C&E或低温手术用于M区域的初级表面BCC.
- 对于L区域的原发性结节BCC,C&E,冷手术或5-FU是优先考虑的.
- 从节省成本的角度来看,表面辐射疗法被确定为巨型BCC的第一线治疗.
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