分析影响产前诊断的腹骨存活率的因素
Işıl Ayhan1, Oya Demirci1, Lütfiye Uygur1
1Department of Perinatology, University of Health Sciences, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Türkiye.
Journal of perinatal medicine
|August 2, 2023
概括
在产前诊断的腹影响生存率. 相关的骨异常和分阶段的手术修复会对产后结果产生负面影响,增加死亡风险.
科学领域:
- 周围生理学 周围生理学
- 胎儿医学 胎儿医学
- 儿科手术 儿科手术
背景情况:
- 腹腔是一种先天性腹壁缺陷,结果各不相同.
- 产前诊断允许早期评估和管理规划.
- 了解影响生存的因素对于临床实践至关重要.
研究的目的:
- 为了确定影响产前诊断的生存的因素omphalocele.
- 为了确定OMPHALOCELE病例中遗传异常的预测因素.
- 分析骨和特定异常群体之间的关联.
主要方法:
- 对产前诊断的乳头病例进行了回顾性观察性研究.
- 对人口统计数据的分析,腹的特征,遗传检测和结果.
- 包括69名在转诊中心的围产科诊所诊断的胎儿.
主要成果:
- 总生存率为73.9%;与孤立病例 (85.7%) 相比,与相关异常 (71.7%) 相关的病例的生存率较低.
- 常见的相关异常包括心脏缺陷 (42%),胎盘/带问题 (28.9%) 和骨缺陷 (27.5%).
- 骨异常和分阶段的手术修复与增加产后死亡风险有关 (分别为OR:4.6和10.3).
结论:
- 相关的骨异常与omphalocele的产后存活率有负面关联.
- 阶段性手术修复也与产后存活有负面关联.
- 这些因素显著增加了出生后死亡的风险.
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