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Updated: Jul 16, 2026

Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure
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使用转基因斑马鱼模型确定化学诱导的面异常的不良结果途径 (AOP)

Shujie Liu1, Toru Kawanishi2,3, Atsuko Shimada2

  • 1R&D, Safety Science Research, Kao Corporation, Tochigi 321-3497, Japan.

Toxicological sciences : an official journal of the Society of Toxicology
|August 2, 2023
PubMed
概括

研究人员开发了斑马鱼记者线来可视化神经细胞 (CNCC),识别面异常的不良结果途径 (AOP). 这种模型有助于预测由原体引起的出生缺陷.

关键词:
不良结果路径 (AOP)头骨神经的细胞是脑神经的细胞.头骨脸部异常情况它们具有原性地质.转基因斑马鱼模型

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Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...