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Updated: Jul 20, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Published on: October 26, 2015

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中性胺酶活性部位抑制剂化学型和结合方式

Nicolas Coant1, John D Bickel2, Ronald Rahaim3

  • 1Stony Brook University Cancer Center, Stony Brook University, Stony Brook, NY 11794, USA.

Bioorganic chemistry
|August 2, 2023
PubMed
概括

研究人员开发了新的中性胺酶 (nCDase) 抑制剂,这些抑制剂不是胺基模仿剂. 这些化合物显示出更好的效能和可溶性,为涉及胺代谢的疾病提供了一个有希望的新疗法途径.

关键词:
结肠直肠癌是一种癌症.中性胺酶中性胺酶中性胺酶中性中性胺酶抑制剂 中性胺酶抑制剂在 nCDase 中.

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