通过含有蛋白质的SET域在植物中的表观遗传控制的动力学:结构和功能见解
Sushmita Seni1, Roshan Kumar Singh1, Manoj Prasad2
1National Institute of Plant Genome Research (NIPGR), Aruna Asaf Ali Marg, New Delhi 110067, India.
Biochimica et biophysica acta. Gene regulatory mechanisms
|August 2, 2023
概括
植物SET域组 (SDG) 蛋白通过基因组甲基化,一个关键的表观遗传机制,调节基因表达. 本综述详细介绍了可持续发展目标的多样性,结构以及它们在植物发展和环境适应方面的作用.
科学领域:
- 植物生物学 植物生物学
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
- 分子生物学分子生物学
背景情况:
- 植物利用染色体的结构动力学来控制基因表达以适应和发育.
- 基因组甲基化,一个关键的表观遗传标记,是由基因组 lysine 甲基转移酶 (HKMTs) 催化,具有保存的 SET 域.
- 植物SET域组 (SDG) 蛋白质是多样化的,被分类为具有特定染色体功能的保存进化类.
研究的目的:
- 审查植物SET域组 (SDG) 蛋白质的多样性和结构性质.
- 总结含有蛋白质的SDG领域在植物发育中的功能.
- 突出可持续发展目标在植物对环境刺激的反应中的作用.
主要方法:
- 文献综述侧重于植物SDG蛋白质.
- 对可持续发展目标的结构性质和进化性保护的分析.
- 在工厂过程中关于SDG角色的功能数据的编制.
主要成果:
- 可持续发展目标是多样化的,具有保护的领域,经常在蛋白质复合体中运行.
- 通过SDG介导的基因素甲基化会影响染色质结构和基因表达.
- 可持续发展目标功能对于植物发育过程和环境反应至关重要,包括替代拼接.
结论:
- 植物可持续发展目标代表了一种多样化的表观遗传调节器家族,在发展和环境适应方面发挥着重要作用.
- 了解可持续发展目标的多样性和功能是解读植物表观遗传机制的关键.
- 对可持续发展目标复合体及其目标的进一步研究将揭示植物基因调节.
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