身体活动与中国慢性病风险的关联:基于人口的队列研究
Kexiang Shi1, Yunqing Zhu1, Jun Lv2
1Department of Epidemiology & Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China.
Journal of sport and health science
|August 2, 2023
概括
身体活动 (PA) 与慢性病 (CKD) 的风险降低有关. 增加的非职业性,低强度和中度至强度的PA都显示出对CKD的保护作用,包括糖尿病脏病和高血压脏病.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 关于体力活动 (PA) 与慢性病 (CKD) 风险之间的关联信息有限.
- 本研究研究了在中国成年人群中不同类型和强度的PA和CKD之间的关系.
研究的目的:
- 探索总体,域特定和强度特定的PA与中国CKD及其亚型风险的关联.
- 为了确定不同类型和强度的体力活动是否对CKD风险有剂量依赖的影响.
主要方法:
- 一项大型队列研究涉及475,376名30-79岁的成年人,来自中国Kadoorie生物银行 (2004-2008).
- 身体活动使用面试官管理的问卷进行评估,并以每天MET小时 (MET-h/day) 量化.
- 考克斯回归模型被用来分析PA水平和发生的CKD之间的关联,平均随访时间为12.1年.
主要成果:
- 总共记录了5415例发生的CKD病例,包括糖尿病病 (DKD) 和高血压脏病 (HTN).
- 较高的总PA水平显着与慢性脏病风险降低相关 (HR:0.83;95% CI:0.75-0.92).
- 特定类型的PA,包括非职业,低强度和中度至强度的PA,也与CKD风险相反相关.
结论:
- 身体活动,包括非职业,低强度和中等到强烈强度的形式,表明与CKD风险的反向关系.
- 这些关联被发现是剂量依赖的,这表明更多的体育活动给予了对CKD (包括DKD和HTN) 的更大保护.
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