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Updated: Jul 20, 2025

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确定性早期内体成长来自于一个随机的触发和转换机制

Harrison M York1, Kunaal Joshi2, Charles S Wright2

  • 1Monash Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton/Melbourne, VIC, 3800, Australia. harrison.york@monash.edu.

Nature communications
|August 2, 2023
PubMed
概括

细胞内体成熟对于货物运输至关重要,是由非常早期 (APPL1阳性) 和早期 (EEA1阳性) 内体之间的直接接触驱动的,而不是自主事件. 这种相互作用是由蛋白质EEA1调解的,控制成熟时间和种群水平.

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