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Updated: Jul 20, 2025

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

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在CHD1L附近的非洲特异性人类遗传变异与HIV-1负载相关

Paul J McLaren1,2, Immacolata Porreca3, Gennaro Iaconis4

  • 1Sexually Transmitted and Blood-Borne Infections Division at JC Wilt Infectious Diseases Research Centre, National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada. paul.mclaren@phac-aspc.gc.ca.

Nature
|August 2, 2023
PubMed
概括

研究人员在非洲血统的人群中发现了一种新的基因变异,该变异能降低HIV-1病毒载量. 靠近CHD1L基因的这种非洲特异性变体可能为控制1型人类免疫缺陷病毒提供新的治疗点.

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