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Updated: Jul 20, 2025

A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
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依赖STING/ACSL4轴的铁和炎症促进高血压相关的慢性病

Li Gao1, Junsheng Zhang2, Tingting Yang3

  • 1Department of Nephropathy, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; Center for Scientific Research of Anhui Medical University, Hefei 230022, China.

Molecular therapy : the journal of the American Society of Gene Therapy
|August 3, 2023
PubMed
概括

高血压通过导致线粒体DNA (mtDNA) 泄漏,激活STING通路,并促进炎症和纤维化而损害脏. 针对STING/ACSL4轴可能为与高血压相关的慢性病 (CKD) 提供一种新的治疗方法.

关键词:
ангиотензин II 的使用慢性脏疾病 慢性脏疾病这种高血压,高血压.这是一种炎症炎症炎症炎症.造成末器官损伤.干扰素基因的刺激剂.

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