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Updated: Jul 20, 2025

Detection of Rare Mutations in CtDNA Using Next Generation Sequencing
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TRcaller:一种用于大规模并行测序的精确和超快的并联重复变异基因型识别的新型工具,读取大量并行测序

Xuewen Wang1, Meng Huang1, Bruce Budowle1,2

  • 1Center for Human Identification, University of North Texas Health Science Center, Fort Worth, TX, United States.

Frontiers in genetics
|August 3, 2023
PubMed
概括

TRcaller使用一种新的算法,从DNA序列中准确地生成并列重复 (TR) 的基因型. 这种生物信息学工具显著提高了短读和长读测序数据的准确性和速度.

关键词:
疾病 TR 基因型鉴定法医STR识别识别STR识别高吞吐量测序的测序串联重复重复的重复变体呼叫者变体呼叫者

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