酸牙膏在成年人中预防牙的影响:18个月的双盲随机临床试验
Elzbieta Paszynska1, Malgorzata Pawinska2, Joachim Enax3
1Department of Integrated Dentistry, Poznan University of Medical Sciences, Poznan, Poland.
Frontiers in public health
|August 3, 2023
概括
一项临床试验发现,酸牙膏是化物牙膏的安全有效替代品,可以预防牙损伤. 这种无化物选择在减少成年人牙腐烂方面表现出类似的结果.
科学领域:
- 牙科 牙科是指牙科的专业.
- 公共卫生 公共卫生
- 生物材料是一种生物材料.
背景情况:
- 牙损是一个重要的全球公共卫生问题.
- 化牙膏在牙预防中的有效性已经得到了很好的证实.
- 为了应对公共卫生挑战,正在研究替代性抗菌剂.
研究的目的:
- 为了比较无化物氧酸盐牙膏与标准化牙膏的防腐蚀效果.
- 评估酸作为口腔卫生产品中潜在的抗菌剂.
主要方法:
- 进行了一项为期18个月的双盲随机临床试验.
- 主要终点是受试者在衰变缺失填充表面 (DMFS) 指数没有增加的百分比.
- 用预定义的利率 (Δ ≤ 20%) 进行了非劣势分析.
主要成果:
- 189名成年人被纳入治疗意向分析.
- 每项协议分析显示,89.3%的酸组和87.4%的化物组没有增加DMFS指数.
- 发现,化牙膏在预防牙方面与化牙膏相比,效果不劣.
结论:
- 氧酸盐证明了作为抗 agent 的安全性和有效性.
- 无化物氧酸盐牙膏是预防牙的可行选择.
- 进一步的研究可能会支持将酸合并到口腔护理程序中.
关键词:
腐烂的缺失填充表面 (DMFS) 指数.成年人成年人成年人成年人成年人牙损 牙损 牙损 牙损 是一种化物化物是什么?氧帕提特是一种氧帕提特.公共卫生公共卫生.随机临床试验 (RCT) 是一种随机临床试验.牙膏是一种牙膏.更多相关视频
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