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患有COVID-19住院患者的严重自发性血液瘤

Silvia Otero-Rodriguez¹, Cristina Guillen², Maria Mataix³

¹Infectious Diseases Unit, Alicante General University Hospital-Alicante Institute of Sanitary and Biomedical Research (ISABIAL), Alicante, Spain.

International journal of clinical practice

|August 3, 2023

概括

严重自发出血是COVID-19的罕见但严重的并发症,比非COVID-19患者更频繁. 这种情况,通常需要栓塞,与高死亡率有关.

科学领域:

传染性疾病传染性疾病
血液学血液学血液学
放射学放射学是一门学科.

背景情况:

COVID-19与各种并发症有关,包括出血事件.
严重的自发性血液瘤是一种不常见但在COVID-19患者中观察到的显著并发症.

研究的目的:

描述COVID-19患者严重自发性血液瘤的流行病学,临床,实验室和放射学特征.
描述医疗治疗和结果,包括栓塞和死亡率,在这个患者队列.

主要方法:

对被诊断患有严重自发出血的住院COVID-19患者的回顾性研究.
纳入标准:严重自发出血并发症的诊断,计算机断层扫描血管学 (CTA) 治疗.
研究期:2020年3月1日至2022年2月28日. 使用逻辑回归来分析死亡率关联的基线变量.

主要成果:

20名患者 (每1000名COVID-19患者中有8.1人) 呈现出严重的自发肌内出血.
平均年龄68.5岁,并发病率高 (查尔森指数4.5的中位数),高剂量肝素的95%.
所有患者都接受了栓塞;45%的死亡率. 没有特定的死亡风险因素被发现.

结论:

严重出血,虽然在COVID-19中不常见,但比非COVID-19患者更频繁.
这种并发症通常需要栓塞,并与高死亡率有关.
可能需要进一步的研究来确定特定的风险因素和优化管理.

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