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一项关于坚持地中海式饮食与乳腺癌之间的关联的病例控制研究
Omid Sadeghi1, Niloofar Eshaghian2, Sanaz Benisi-Kohansal3
1Nutrition and Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
坚持地中海饮食显著降低了伊朗妇女患乳腺癌的风险. 这种饮食模式与患乳腺癌的可能性降低了57%,特别是在绝经后的妇女中.
科学领域:
- 流行病学 流行病学
- 营养科学 营养科学
- 在瘤学瘤学.
背景情况:
- 乳腺癌是中东国家的主要癌症,但饮食数据有限.
- 之前的研究主要集中在西方人群上,在中东地区了解饮食与乳腺癌的联系存在差距.
- 这项研究通过调查地中海饮食对伊朗妇女乳腺癌的作用来解决数据稀缺的问题.
研究的目的:
- 检查坚持地中海式饮食与患乳腺癌的风险之间的关联.
- 提供来自中东人口的关键数据,其中乳腺癌发病率很高.
- 为了确定伊朗妇女的潜在的饮食保护因素,防止乳腺癌.
主要方法:
- 一项基于人口的病例控制研究,涉及350例乳腺癌病例和700个匹配的对照.
- 饮食摄入量使用106项半定量食品频率问卷 (SQ-FFQ) 进行评估.
- 计算了地中海饮食得分,并对混变量进行了控制.
主要成果:
- 在地中海饮食和乳腺癌之间发现了显著的反向关联.
- 地中海饮食得分最高的第三位女性患乳腺癌的几率降低了57% (OR:0.43,95% CI:0.28-0.67).
- 这种保护性关联在绝经后的妇女中是显著的,但在绝经前的妇女中并非如此.
结论:
- 坚持地中海饮食模式与伊朗女性乳腺癌的几率降低有关.
- 这些发现表明地中海饮食对抗乳腺癌的潜在保护作用.
- 建议进行进一步的前性研究,以证实这些发现并探索相关机制.
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