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Updated: Jul 20, 2025

Biotinylated Cell-penetrating Peptides to Study Intracellular Protein-protein Interactions
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Published on: December 20, 2017

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模拟人类STING的C端尾部及其与结合激酶1的相互作用

Rahaf Ata Ouda Al-Masri1, Hajara Audu-Bida1, Şebnem Eşsiz1

  • 1Kadir Has University, Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, İstanbul, Turkey.

Turkish journal of biology = Turk biyoloji dergisi
|August 3, 2023
PubMed
概括

这项研究模拟了干扰素基因刺激器 (STING) 的C端尾 (CTT) 在活跃和不活跃状态. 与TBK1的对接揭示了活跃的STING CTT模型更类似于冷EM结构.

关键词:
在C-终端尾部 (CTT) 域.循环建模循环建模坦克结合激酶1 (TBK1) 是一种在 cGAS-cGAMP-STING 路径中.蛋白质与蛋白质的对接干扰素基因 (STING) 的刺激器

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