基于临床因素预测性结肠炎患者的日历年再入院的诺米克图
Ying Xiang1, Ying Yuan1, Jinyan Liu1
1Department of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu Province, China.
Therapeutic advances in gastroenterology
|August 3, 2023
概括
这项研究开发了一种名谱来预测性结肠炎 (UC) 再入院,确定关键风险因素,如并发症和皮质类固醇使用. 该工具有助于将UC患者分为不同的风险组,以进行量身定制的管理.
科学领域:
- 胃肠病学 胃肠病学
- 临床医学 临床医学
- 医疗信息学 医疗信息学
背景情况:
- 性结肠炎 (UC) 的非计划性再入院表明疾病的严重程度和治疗的无效性.
- 预测再接收对于改善患者预后和管理医疗保健资源至关重要.
研究的目的:
- 为了确定预后变量来预测在一年内与UC相关的计划外再接收.
- 开发和验证用于预测UC再接收风险的名录.
主要方法:
- 回顾性队列研究分析了UC患者的电子病历 (2014年1月 - 2021年6月).
- 对人口统计,并发病,病史,随访,内镜检查和组织病理学的综合分析.
- 多变量考克斯分析和名图开发,并进行内部和外部验证.
主要成果:
- 一年的非计划性UC再接收率为20.8%.
- 关键预测因素包括埃利克沙瑟并发症指数,定期随访,皮质类固醇使用,C反应性蛋白水平和UC内镜严重性指数.
- 在预测再录取时,名图显示出高准确度 (一致性指数为0.784-0.837).
结论:
- 一个经过验证的名图有效地预测了UC患者1年的再入院风险.
- 根据名谱得分,UC患者可以分为低,高和极高风险组.
- 高危UC患者可能会从密集治疗和频繁的门诊随访中受益.
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