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一项为期5年的随访研究,探索与公共汽车司机快速功能下降相关的因素
Yanxia Wu1, Qianqian Chen2, Qionghua Zhang1
1Health Management Center, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, People's Republic of China.
公交车司机面临更高的功能障碍的风险. 年龄,较高的基线EGFR和血清尿酸 (SUA) 水平的增加与五年内功能快速下降有关.
科学领域:
- 职业健康 职业健康 职业健康
- 腎臟病學 (nephrology) 是一種醫學專業.
- 流行病学 流行病学
背景情况:
- 公共汽车司机由于职业压力而增加功能障碍的风险.
- 在这个人群中,导致功能加速下降的因素仍未得到充分探索.
研究的目的:
- 确定与公共汽车司机功能快速下降相关的因素.
- 为了检查血清尿酸 (SUA) 和估计的淋巴细胞过率 (eGFR) 随着时间的推移而变化的关系.
主要方法:
- 在中国深进行了一项为期五年的队列研究 (2017-2021),涉及832名基线功能正常的公共汽车司机.
- 根据eGFR变化的四分位数分析了受试者;快速下降被定义为最高四分位数.
- 用单变量和多变量逻辑回归来确定影响因素.
主要成果:
- 2017年高尿路血症的患病率为37.7%,2021年为40.5%.
- 观察到5年的EGFR中位数下降6.72毫升/分钟/1.73平方米.
- 增加的SUA水平与最大的eGFR下降相关. 年龄,基线eGFR升高和SUA增加是快速eGFR下降的重要风险因素.
结论:
- 在公共汽车司机中高发性高尿路血症需要医疗照顾.
- 年龄,基线eGFR升高和SUA增加是快速eGFR下降的关键风险因素.
- 这些发现支持有针对性的预防策略,以减轻公共汽车司机功能下降的风险.
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