[影响下 gingival 状细胞癌预后的临床因素]
1Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & NHC Research Center of Engineering and Technology for Computerized Dentistry & NMPA Key Laboratory for Dental Materials, Beijing 100081, China.
概括
下牙平细胞癌 (LGSCC) 的预后随着下部侵袭的增加而恶化. N阶段和局部复发是关键的预后因素,后部瘤显示出更高的宫淋巴结转移率.
科学领域:
- 在瘤学瘤学.
- 在口腔外科手术.
- 头部和部癌症研究研究
背景情况:
- 下牙平细胞癌 (LGSCC) 在治疗和预后方面提出了独特的挑战.
- 了解影响局部复发和生存的因素对于有效管理至关重要.
研究的目的:
- 确定影响LGSCC患者局部复发和生存的临床因素.
- 评估骨侵袭作为LGSCC的独立预后指标.
主要方法:
- 对104名LGSCC患者的回顾性分析,随访时间超过3年.
- 术前成像 (CT,全景放射) 评估了骨侵袭深度.
- 分析了瘤的位置 (前与后) 和N阶段.
主要成果:
- 一年,三年和五年生存率分别为91%,84%和82%.
- 宫淋巴结转移发生在32.7%的患者中,较高的是下后部瘤 (36.4%) 与前部瘤 (12.5%).
- N 阶段和局部复发是显著的预后因素 (P < 0.05).
结论:
- 增加下部入侵与较差的LGSCC预后相关.
- N阶段和局部复发是确定的预后风险因素.
- 瘤的位置影响了宫淋巴结转移的风险,这表明了量身定制的手术策略.
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