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用三甲基组进行RNA标记的进展

Clemens Eichler1, Maximilian Himmelstoß1, Raphael Plangger1

  • 1Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.

Chemistry (Weinheim an der Bergstrasse, Germany)
|August 3, 2023
PubMed
概括

这项研究引入了新的标记RNA构建块,用于增强RNA结构和相互作用的NMR分析. 这些修改对治疗性寡核酸有希望,并完成了所有标准核基的集合.

关键词:
19F 核磁共振光谱法 19F 核磁共振光谱法固相合成RNA的固相合成核酸的修改 核酸的修改氧核酸类的部分.三甲基化.

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