便秘和腹腔透析中的临床结果:泰国PDOPPS的结果
Guttiga Halue1, Huttaporn Tharapanich2, Jeerath Phannajit3,4
1Department of Medicine, Phayao Hospital, Phayao, Thailand.
Nephrology (Carlton, Vic.)
|August 3, 2023
概括
在腹膜透析 (PD) 患者中,患者报告的便秘是常见的,并且与腹膜炎和死亡的风险更高有关. 需要进一步的研究,以找到PD患者有效的便秘治疗方法.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 胃肠病学 胃肠病学
- 临床结果研究研究
背景情况:
- 患者报告的结果测量 (PROM) 对于预测腹腔透析 (PD) 的临床结果至关重要.
- 这项研究研究了患者报告的便秘和PD患者的临床结果之间的关系.
研究的目的:
- 探索患者报告的便秘与临床结果之间的关联,包括腹透析患者的死亡率,血液透析转移和腹膜炎.
主要方法:
- 使用布里斯托尔便形式尺度 (BSFS) 和便严重程度评分 (CSS) 评估了在22个医疗机构的729名PD患者 (2014-2017) 中的便秘.
- 考克斯比例危险回归模型用于分析便秘和临床结果之间的关联.
主要成果:
- 便秘影响了13%的PD患者,更常见的是老年人,照顾者依赖的糖尿病患者和较差的营养状况.
- 自我报告的便秘与腹膜炎的增加率和死亡率有显著的相关性.
- 在便秘和血液透析转移之间没有发现显著的关联.
结论:
- 患者报告的便秘是PD患者腹膜炎和死亡率的独立风险因素.
- 这些发现凸显了需要干预措施来管理这个人群中便秘的需要.
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