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间歇性禁食改善了非酒精性脂肪肝疾病中的肝脏终点:系统性审查和元分析
Marcia Lange1, Devika Nadkarni1, Lily Martin1
1Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Hepatology communications
|August 3, 2023
概括
间歇性禁食 (IF) 对改善非酒精性脂肪性肝病 (NAFLD) 的成年人改善肝脏健康和促进体重减轻有希望. 这一系统性审查表明,IF对NAFLD患者的关键健康标志物产生积极影响.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢疾病 代谢疾病
- 营养科学 营养科学
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 是全球最常见的肝病,但缺乏FDA批准的治疗方法.
- 目前的建议侧重于通过热量限制和体育活动减肥.
- 间歇性禁食 (IF) 是一种潜在的替代策略,具有额外的心脏代谢益处.
结论:
- 中等到高质量的证据表明,IF可以改善肝脏终点,并促进NAFLD患者的体重减轻.
- 需要进一步进行更长时间的大规模随机对照试验来证实这些发现.
- 国际融资可能是一个可行的补充策略来管理NAFLD.
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