运动训练和补充氧气对慢性阻塞性肺部疾病中的外周肌肉的影响:一项随机对照试验
Daniel Neunhäuserer, Martin Hudelmaier1, David Niederseer
1Institute of Anatomy and Cell Biology, Paracelsus Medical University of Salzburg, Salzburg, AUSTRIA.
Medicine and science in sports and exercise
|August 3, 2023
概括
补充氧气增强了慢性阻塞性肺病患者的运动训练益处. 它提高了肌肉的强度和大小,可能通过抵消运动引起的缺氧和促进适应.
科学领域:
- 肺部医学 肺部医学
- 运动生理学 运动生理学
- 肌肉适应 肌肉适应
背景情况:
- 慢性阻塞性肺病 (COPD) 治疗包括运动训练.
- 骨肌肉功能障碍和COPD适应异质性尚未完全理解.
- 研究补充氧气在COPD患者运动训练中的作用.
研究的目的:
- 研究运动训练和补充氧气对COPD患者功能和结构外围肌肉适应的影响.
- 评估补充氧气如何影响运动能力,肌肉强度和四头肌横截面积 (CSA) 与医疗空气相比.
主要方法:
- 前性,随机,受控,双盲研究.
- 28名非低血压性慢性肺炎患者接受了为期6周的综合耐力和力量训练.
- 干预措施包括在训练期间呼吸补充氧气或医疗空气.
主要成果:
- 运动训练显著增加了功能能力,有氧能力,运动耐受性,四头肌强度和CSA.
- 与医疗空气相比,补充氧气显著提高了培训对峰值工作率的影响.
- 只有在补充氧气的训练组中才观察到CSA的显著增加;氧气和运动诱导的脱和肌肉增长相反.
结论:
- 慢性肺炎患者的异质肌肉适应似乎受到补充氧气和运动诱导的缺氧的影响.
- 补充氧气可以促进肌肉训练适应,特别是在四肢肌肉功能障碍.
- 这有助于提高COPD患者在最大有氧和功能能力方面的训练反应.
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