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Updated: Jul 20, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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侧组 转换α7尼古丁受体激动剂乙昆利丁为I型阳性体调节器

Franco Viscarra1,2, Juan Facundo Chrestia3, Yaima Sanchez4

  • 1Department of Biological and Medical Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, U.K.

ACS chemical neuroscience
|August 3, 2023
PubMed
概括

研究人员合成了新型乙烯基氨酸以研究尼古丁乙胆受体 (nAChR) 功能. 干6已成为α7nAChR亚型的强有力的I型阳性全调节器 (PAM-I).

关键词:
乙烯基核化物.化学合成 化学合成分子对接的分子对接.分子动力学分子动力学积极的全调节器.单频道录音的记录.电压灯的电压

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