血病学实践中的梅毒:一个诊断挑战
Efrain Gutierrez-Lanz1, Lauren B Smith, Anamarija M Perry1
1From the Department of Pathology, University of Michigan, Ann Arbor.
Archives of pathology & laboratory medicine
|August 3, 2023
概括
梅毒 (Treponema pallidum) 正在重新出现,在外科病理学中提出了诊断挑战. 识别关键的淋巴结和气消化道特征对于准确的诊断至关重要.
科学领域:
- 病理学 病理学 病理学
- 传染性疾病 传染性疾病
- 手术病理学手术病理学
背景情况:
- 梅毒是由Treponema pallidum引起的,是一种重新出现的传染病.
- 在外科病理学和血液病理学中频率越来越高,经常呈现为淋巴腺病.
- 可以模仿淋巴结和气消化道中的淋巴瘤与淋巴细胞细胞透物.
研究的目的:
- 概述梅毒性淋巴腺炎和空气消化道病变的组织学特征.
- 审查差异诊断和诊断陷.
- 强调在具有挑战性的病例中考虑梅毒的重要性.
主要方法:
- 使用PubMed搜索进行文献综述.
主要成果:
- 梅毒性淋巴腺炎显示缩的囊,富含血细胞的透物,反应性增生和血管炎.
- 空气消化道梅毒呈现出富含血细胞的透物.
- 对T pallidum的免疫组织化学是有用的,但具有交叉反应性.
结论:
- 在淋巴结和气消化道中诊断梅毒是具有挑战性的,因为形态的变化和低临床怀疑.
- 差异诊断的范围很广,包括反应性,传染性和瘤性疾病.
- 病理学家必须了解梅毒的特征,才能将其纳入差异诊断.
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