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Updated: Jul 20, 2025

Assessment of Myofilament Ca2+ Sensitivity Underlying Cardiac Excitation-contraction Coupling
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二元离子作为心脏肌酸酶结合蛋白C中的碳化介质

Christina Bergonzo1, Baikuntha Aryal2, V Ashutosh Rao2

  • 1Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, the University of Maryland, 9600 Gudelsky Way, Rockville, MD, 20850, USA.

Journal of molecular graphics & modelling
|August 3, 2023
PubMed
概括

化疗药物毒性可能源于金属诱导的心脏肌结合蛋白C (cMyBP-C) 的损伤. 这项研究揭示了cMyBP-C附近的金属离子可能会破坏其活性蛋白结合,影响心脏功能.

关键词:
金属离子诱导的ROSS分子动力学分子动力学蛋白质碳基化蛋白质的碳基化.cMyBP-C 的时间.

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