复杂的起源,进化和多样化非正规组织的OVATE-OFP和OVATE-LikeOFP基因对跨胚胎细胞
Nishu Chahar1, Meenakshi Dangwal1, Sandip Das1
1Department of Botany, University of Delhi, Delhi 110 007, India.
Gene
|August 3, 2023
概括
卵子家族蛋白 (OFP) 基因家族起源于陆地植物,在种子植物中演变为头对头的基因对. 这种组织,特别是在Brassicaceae中,可以通过共享的促进体实现复杂的转录调节.
科学领域:
- 植物分子生物学 植物分子生物学
- 进化基因组学是进化的基因组学.
- 基因家族的演化 基因家族的演化
背景情况:
- 卵巢家族蛋白 (OFP) 是植物特有的负转录调节剂.
- 之前的研究集中在OFP家族的大小和扩张上,在理解复杂基因组织的起源方面留下了一个空白,比如头对头安排.
- 头对头基因对可能允许通过共享的双向促进体共同调节.
研究的目的:
- 在Archaeplastida中调查两对OFP基因对 (AtOFP2-AtOFP17和AtOFP4-AtOFP20) 的起源,组织和演变.
- 确定这些OFP基因对的进化史和遗传学关系.
- 探索非正规组织的OFP基因中转录协调的潜力.
主要方法:
- 进行比较的基因组学.
- 遗传学重建的研究.
- 祖先国家重建的重建.
- 合成分析是指合成分析.
- 复制数分析 复制数分析
主要成果:
- 祖先的OFP2,OFP4,OFP17和OFP20很可能是在早期的陆地植物 (胚胎植物) 中演变的,在Rhodophyta和Chlorophyta中不存在.
- OFP基因家族起源于Bryophyta并扩展,头对头组织出现在Spermatophyta中.
- 头对头的基因对起源于体 (OVATE-OFP同类物) 中,在 Brassicaceae ~32-54 MYA 中进行重复,创建了AtOFP2-AtOFP17和AtOFP4-AtOFP20等同物.
- 而AtOFP2-AtOFP17基因对似乎是血管苗的祖先.
结论:
- 这项研究阐明了两个头对头的OFP基因对的进化轨迹,包括它们的OVATE域的变异.
- 非正典的头对头组织,特别是在Brassicaceae中,表明可能通过常见的双向促进器进行复杂的转录调节.
- 这项研究为了解基因结构的演变,转录调节和跨植物系的功能提供了一个框架.
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