在口腔疾病中的唾液生物标志物
1Wenzhou Medical University Renji College, Wenzhou, China.
概括
唾液生物标志物为诊断口腔疾病提供了一种非侵入性方法,例如牙损伤和口腔癌. 本综述详细介绍了它们的收集,分析和诊断应用.
科学领域:
- 生物化学 生物化学
- 生物标志物发现发现
- 口腔医学是指口腔医学.
背景情况:
- 唾液是一种丰富的生物标志物来源,反映了生理和病理条件.
- 非侵入式的唾液采集是连续监测和诊断测试的理想选择.
- 分析技术的进步提高了唾液生物标志物检测的准确性和灵敏性.
研究的目的:
- 审查目前用于确定唾液生物标志物的程序.
- 突出影响生物标志物分析的预分析因素.
- 提供口腔疾病诊断应用的概述.
主要方法:
- 关于唾液生物标志物分析研究的文献综述.
- 讨论分析前的考虑 (采样,储存,预处理).
- 生物标志物确定分析方法的概述.
主要成果:
- 唾液生物标志物对于诊断牙,牙周炎,口腔状细胞癌 (OSCC) 和Sjögren综合征 (SS) 是有价值的.
- 关键的生物标志物包括生长因子,酶,互白蛋白和细胞因子.
- 标准化的预分析程序对于可靠的结果至关重要.
结论:
- 唾液生物标志物分析是早期检测和监测口腔疾病的有希望的工具.
- 进一步的研究可以确定新的唾液生物标志物,以改善诊断.
- 优化的预分析和分析方法对于临床翻译至关重要.
相关概念视频
Salivary Glands and Saliva
758
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
758
Assessment of the Mouth
256
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
256
Oral Cavity
823
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
823
Serum Laboratory Studies, Stool Test, Breath Test
381
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
381


