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在青春期早期,对大脑发育的个体内和个体间的差异进行分析.
Katherine L Bottenhorn1, Carlos Cardenas-Iniguez2, Kathryn L Mills3
1Department of Population and Public Health Sciences, University of Southern California, 1845 N Soto St, Los Angeles, CA 90032, USA; Department of Psychology, Florida International University, 11200 SW 8th St, Miami, FL 33199, USA.
NeuroImage
|August 3, 2023
概括
了解青春期早期的大脑发育是关键. 这项研究揭示了个体中度大脑变化,但强调青春期显著影响大脑发育的可变性,观察到的性别差异有限.
科学领域:
- 发育神经科学的发展神经科学.
- 神经成像是一种神经成像.
- 青少年的大脑发育 青少年的大脑发育
背景情况:
- 人口级神经科学需要了解大脑成熟的变化.
- 纵向研究显示了群体轨迹,但个体差异仍然不清楚.
- 青春期早期是神经发育变化的一个关键时期.
研究的目的:
- 在青春期早期,量化大脑发育的个体内和个体间的变化.
- 检查年龄,性别和青春期如何影响这种变化.
- 提供有关规范性大脑发育及其异质性的见解.
主要方法:
- 利用了青少年大脑认知发展研究 (ABCD) 的数据.
- 分析了宏观结构,微观结构和功能性大脑发育.
- 从9岁到13岁对大脑测量的年度百分比变化进行了检查.
主要成果:
- 发现中度与年龄相关的个体内大脑变化.
- 鉴定了一些皮质措施的个体间变异性与年龄相关的差异.
- 在青春期中期的个体中观察到更大的个体间变异性,在白质发育方面有一些例外.
- 在一些地区,在宏观结构和功能发展方面注意到性别差异,但对男性更大的变异性提供了有限的支持.
结论:
- 突出了青少年早期大脑发育中的个体变异性.
- 揭示了大脑发育异质性的区域差异.
- 促进未来对规范发展和偏差的研究.
- 强调青春期在塑造大脑成熟的个体间差异中的作用.
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