相关实验视频

Updated: Jul 20, 2025

Electromechanical Assessment of Optogenetically Modulated Cardiomyocyte Activity
12:52

Electromechanical Assessment of Optogenetically Modulated Cardiomyocyte Activity

Published on: March 5, 2020

8.3K

光遗传离子在K+再分配的二次模式上有所不同

R Ryley Parrish1,2, Tom Jackson-Taylor1, Juha Voipio3

  • 1Medical School, Newcastle University Biosciences Institute, Newcastle upon Tyne, UK.

Physiological reports
|August 3, 2023
PubMed
概括

像哈洛罗多普辛一样,阿基尔霍多普辛的激活会导致重新分配到细胞中. 激活后细胞外激增的差异表明结合的Cl-和K+挤出,与类似发作事件相关.

关键词:
考古学家罗多普辛在化物 化物 化物化物 - 酸盐 - 携带载体哈洛霍多普辛 (halorhodopsin) 是一种高度氧化物.和是一种

更多相关视频

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain11:20

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain

Published on: May 7, 2018

12.1K
Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue11:08

Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue

Published on: September 5, 2015

13.7K

相关概念视频

Primary Active Transport01:47

Primary Active Transport

In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps that are embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction...
177.9K
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
3.2K
ATP Driven Pumps I: An Overview01:27

ATP Driven Pumps I: An Overview

ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
8.2K
Resting Potential Decay01:15

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane...
4.9K
Non-gated Ion Channels01:24

Non-gated Ion Channels

Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism....
6.9K
The Resting Membrane Potential01:21

The Resting Membrane Potential

Overview
133.0K