在phoQ中的胆固醇抗性突变可以使Klebsiella pneumoniae对IgM介导的补体杀伤敏感

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Sjors P A van der Lans1, Manon Janet-Maitre2,3, Frerich M Masson1

  • 1Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Scientific reports
|August 3, 2023
PubMed
概括

在Klebsiella pneumoniae中的胆固醇耐药性改变了它与免疫系统的相互作用. 发展出耐药性可能会意外地增加对人类血清补充介导杀伤的易感性.

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