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Updated: Jul 20, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

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探索细菌FeS酶DinG的G-四重复结合和解活动

Elisa De Piante1,2, Federica D'Aria2, Luisa M R Napolitano1

  • 1Structural Biology Laboratory, Elettra-Sincrotrone Trieste S.C.p.A, 34149, Trieste, Italy.

Scientific reports
|August 3, 2023
PubMed
概括

细菌的DinG螺旋酶与各种G四复合体 (G4s) 相互作用,但特别解开某些拓. 这项研究揭示了DinG解决了生理学上相关的单分子G4s,即使被连接体稳定,也会影响酶研究.

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