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Updated: Jul 20, 2025

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
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在胰腺β细胞中,SERCA2调节了亲胰岛素的加工和加工酶的成熟.

Hitoshi Iida1,2, Tatsuyoshi Kono3,4,5,6, Chih-Chun Lee3,4,5,6

  • 1Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

Diabetologia
|August 3, 2023
PubMed
概括

贝塔细胞中SERCA2的丧失会通过破坏ER水平和亲胰岛素的贩运来损害胰岛素的处理. 这导致葡萄糖不耐受和增加的亲胰岛素,模仿糖尿病状况.

关键词:
贝塔细胞生物学 贝塔细胞生物学成像学 成像学的信号传输系统细胞内膜网膜是什么 细胞内膜网膜胰岛素分泌的胰岛素分泌.胰岛素合成的方法亲胰岛素加工加工贩卖蛋白质的人口贩运

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