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修改生物制药药物动力学,对口服药物吸收产生科学和监管影响

Nikolaos Alimpertis1,2, Athanasios A Tsekouras2,3, Panos Macheras4,5

  • 1Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.

Pharmaceutical research
|August 3, 2023
PubMed
概括

有限吸收时间 (F.A.T.) 概念重新评估了经典的药物吸收模型,显示%吸收与时间曲线是双线的,而不是指数的. 这影响了生物制药和药物吸收分析的监管指南.

关键词:
生物制药 生物制药 生物制药有限的吸收时间.口服药物 口服药物药物动力学 药物动力学

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