在缺血性中风患者中,营养不良和中风相关肺炎之间的关联
Dongze Li1,2, Yi Liu1,2, Yu Jia3
1West China School of Nursing, Sichuan University/ Department of Emergency Medicine, West China School of Medicine, West China Hospital, Sichuan University, Chengdu, China.
营养不良显著增加了中风相关性肺炎 (SAP) 在缺血性中风 (IS) 患者的风险. 早期营养不良评估对于预测SAP风险和改善患者治疗结果至关重要.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 关键护理医学 关键护理医学
背景情况:
- 营养不良是已知的死亡风险因素在成人缺血性中风 (IS) 患者.
- 关于IS中营养不良和中风相关肺炎 (SAP) 风险之间的关联存在有限的研究.
- 这项研究通过调查营养不良对IS幸存者的SAP发病率的影响来弥补这一差距.
研究的目的:
- 确定营养不良和成人IS患者发展SAP的风险之间的关系.
- 通过使用已建立的营养指数,评估IS患者营养不良的发生率.
- 评估营养不良评估是否改善SAP风险预测模型.
主要方法:
- 从回顾性多中心研究中对915名IS患者进行回顾性分析,以评估缺血性中风 (REMISE) (2020年1月至12月).
- 使用控制营养状况 (CONUT),老年营养风险指数 (GNRI) 和预后营养指数 (PNI) 系统评估营养不良.
- 采用多变量逻辑回归和接收器操作特征 (ROC) 曲线分析.
主要成果:
- 营养不良很普遍,影响了14.75% (PNI),54.1% (CONUT) 和16.2% (GNRI) 的患者.
- 营养不良 (中度/严重) 独立地与所有指数的SAP风险增加有关:PNI (OR 5.038),CONUT (OR 6.941) 和GNRI (OR 2.007).
- 将营养不良指数纳入A2DS2得分,显著提高了SAP预测的准确性.
结论:
- 营养不良在IS患者中很常见,并显著提高SAP风险.
- 营养状况评估对于识别高风险个体和改善SAP预测至关重要.
- 需要进一步的研究来探索针对营养不良的干预措施,以减轻SAP风险.
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