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Updated: Jul 20, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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定义TP53突变在骨髓瘤新生病中的临床影响的新方案

Waled Bahaj1,2, Tariq Kewan1,3, Carmelo Gurnari1,4

  • 1Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, 9620 Carnegie Ave N Building, Building NE6-250, Cleveland, OH, 44106, USA.

Journal of hematology & oncology
|August 3, 2023
PubMed
概括

TP53突变影响癌症存活率. 一个新的算法准确地分类TP53等位体配置,揭示了神秘的双等位体病例,并改善了髓状瘤的预后评估.

关键词:
基失活化是一种基失活化.骨髓状细胞瘤发生病.这是下一代测序.单细胞 DNA 测序 单细胞 DNA 测序有TP53突变的突变.

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