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青春期,月经,怀孕,哺乳期和更年期对慢性尿疹活动的影响
Sinem Ayse Ornek1, Alisa Suroji Alkilinc2, Utkan Kızıltac3
1Department of Dermatology, Health Sciences University Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
Journal of cutaneous medicine and surgery
|August 4, 2023
概括
大多数女性的荷尔蒙变化通常不会影响慢性疹 (CU). 然而,近三分之一的患者在月经周期期间经历了CU症状的恶化.
科学领域:
- 皮肤病学 皮肤病学
- 内分泌学 在内分泌学.
- 免疫学 免疫学 免疫学
背景情况:
- 慢性疹 (CU) 是一种全身性疾病,由持续超过六周的反复发和/或血管定义.
- 性激素在CU病变发生过程中的潜在作用已得到承认,但其临床意义仍然不够详细.
研究的目的:
- 为了研究激素波动在关键生命阶段对慢性疹的过程的影响.
- 检查青春期,月经,怀孕,母乳养和更年期对CU疾病活动的影响.
主要方法:
- 一项涉及111名女性CU患者的横截面问卷研究.
- 数据是在2016-2017年间在奥克梅丹尼培训和研究医院UCARE中心收集的.
- 该问卷评估了患者报告的荷尔蒙变化对CU症状的影响.
主要成果:
- 大多数CU患者报告说,在青春期 (100%),怀孕 (96%),哺乳期 (83.8%) 和更年期 (95.6%) 期间疾病过程没有变化.
- 很大一部分患者 (29%) 在月经前期经历了CU症状的恶化.
- 一个小比例 (4.8%) 报告说,在月经前期期间,CU症状有所改善.
结论:
- 与常见的假设相反,性激素水平的显著变化并没有影响大多数慢性疹病例.
- 一个显著的CU患者子组 (约三分之一) 观察到疾病活动的增加,特别是在月经前期.
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