呼吸暂停与呼吸暂停占主导地位的患者的催眠神经刺激治疗结果
Thomas Z Gao1, Jianing Ma2, Daniel Hall3
1College of Medicine, The Ohio State University, Columbus, Ohio, USA.
概括
这项研究发现,在患有主要是呼吸暂停或呼吸暂停的患者之间,低分泌神经刺激 (HGNS) 治疗结果没有显著差异. 这些发现表明,HGNS的有效性独立于阻塞性睡眠呼吸暂停的呼吸事件类型.
科学领域:
- 睡眠医学 睡眠医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经调节是一种神经调节.
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 的特点是睡眠期间上呼吸道崩.
- 低分泌神经刺激 (HGNS) 是适度至重度OSA的有效治疗方法.
- 呼吸暂停占主导地位与呼吸暂停占主导地位对HGNS结果的影响尚不清楚.
研究的目的:
- 评估呼吸暂停占主导地位和呼吸暂停占主导地位对HGNS治疗结果的意义.
- 为了研究药物诱导睡眠内镜 (DISE) 和HGNS疗效期间呼吸道崩模式之间的关系.
主要方法:
- 一个追溯的病例系列,包括216名接受了DISE和HGNS植入的患者.
- 呼吸暂停-呼吸暂停指数 (AHI) 根据4%的标准计算,不包括中央呼吸暂停.
- 统计分析包括后勤/线性回归和克鲁斯卡尔-瓦利斯测试,以比较结果和崩模式.
主要成果:
- 在呼吸暂停占主导地位 (n=63) 和呼吸暂停占主导地位 (n=153) 的群体之间没有显著的人口差异.
- 在两组之间,1年后的HGNS结果是相似的.
- 在没有口腔大喉塌陷的患者中观察到较低的缺血指数.
结论:
- 呼吸暂停占主导地位或呼吸暂停占主导地位并没有显著影响HGNS治疗结果.
- DISE解剖学和HGNS疗效似乎独立于主要的呼吸事件类型.
- 这些发现与其他OSA治疗方法 (如CPAP和下推进) 的研究一致.
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