在体积调节离子通道 (VRAC) 研究的趋势:2014年至2022年的可视化和文献识别分析
Tianbao Liu1,2,3, Yin Li4, Dawei Wang1,2,3,5
1Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Frontiers in pharmacology
|August 4, 2023
概括
这份图书统计分析显示,美国是VRAC研究的领导者,其中Thomas J. Jentsch是主要作者. 体积调节的离子通道 (VRAC) 在细胞过程和疾病中至关重要,为未来的研究方向提供了方向.
科学领域:
- 生理学 生理学 生理学
- 分子生物学分子生物学
- 生物化学 生物化学
背景情况:
- 体积调节的离子通道 (VRAC) 在细胞平衡和各种生理过程中起着至关重要的作用.
- 了解VRAC的研究环境对于推进细胞信号传导和疾病机制的知识至关重要.
研究的目的:
- 从2014年到2022年对VRAC的科学成果进行文献计量分析.
- 在VRAC研究中确定领先的国家,机构,作者和关键研究主题.
主要方法:
- 从科学网络 (2014-2022) 获取的278篇文章和评论的图书统计分析.
- 使用VOSviewer进行网络可视化 (国家,机构,作者) 和CiteSpace进行关键字和引用分析.
- 分析了期刊的共同引用,文档引用和关键字的共同出现.
主要成果:
- 美国在出版物方面领先;哥本哈根大学是顶级机构;托马斯·J·詹茨是最多产的作者.
- 关键发现包括识别LRRC8异构体作为VRAC组件 (Voss等人,2014).
- VRAC涉及细胞生长,细胞亡,运输 (阴离子,氧化物),离子通道 (TMEM16A,CFTR),疾病 (,癌症) 和耐药性.
结论:
- VRAC研究是一个充满活力和不断扩大的领域,具有重大全球兴趣.
- 本文献统计概述为VRAC研究提供了全面的视角,指导未来的调查.
- 该研究强调了VRAC在各种生理和病理过程中的参与,强调了其治疗潜力.
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