慢性髓性白血病的多学科管理改善了SCORE测量的心血管风险
Alberto Blanco Sánchez1, Rodrigo Gil Manso1, Gonzalo Carreño-Tarragona1
1Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Frontiers in pharmacology
|August 4, 2023
概括
在慢性髓性白血病 (CML) 患者中,通过专业咨询管理心血管风险因素,通过治疗氨酸激酶抑制剂 (TKI) 的患者显著改善了结果. 这种方法有助于减少心血管事件并有效管理风险因素.
科学领域:
- 心脏病学 心脏病学
- 血液学 血液学 血液学
- 在瘤学瘤学.
背景情况:
- 心血管事件是慢性髓性白血病 (CML) 患者在氨酸激酶抑制剂 (TKI) 治疗中的主要长期并发症.
- 优化TKI选择和控制心血管风险因素对于减轻这种患者群体的并发症至关重要.
研究的目的:
- 在诊断时和随访期间在专业心血管风险咨询中评估CML患者的心血管风险.
- 分析风险因素管理对接受TKIs的CML患者心血管健康的影响.
主要方法:
- 从2015年至2018年,对35名用TCI治疗的CML患者进行了回顾性分析.
- 在诊断和随访期间评估心血管风险因素和SCORE.
- 在专业心血管风险咨询中对干预措施的评估.
主要成果:
- 在诊断时,60%的患者有风险因素,20%的患者被SCORE分类为高/非常高风险.
- 在随访期间,高血压是主要的不良事件 (23%).
- 观察到显著的改善:66%的人戒烟,95%的人控制血压,50%的人控制糖尿病,76%的人控制体重,92%的人控制脂质失调症. 在很大比例的患者中,SCORE的降低被注意到.
结论:
- 在专业咨询中进行后续检查对于在TKI治疗中CML患者的心血管风险因素的管理是有益的.
- 积极管理风险因素可以减少心血管并发症,并改善CML患者的整体健康结果.
关键词:
获得得分的得分心血管疾病的风险.慢性髓性白血病 (CML) 是一种疾病.冠状动脉疾病是一种冠状动脉疾病.多学科的管理管理.血栓栓塞栓性疾病是一种血栓塞栓性疾病.铁氨酸激酶抑制剂 (TKI) 的使用更多相关视频
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