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长期消化不良症状 - - 是COVID-19大流行病的另一个后果吗?
Anna Nazarewska1, Konrad Lewandowski1, Magdalena Kaniewska1
1Clinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland.
在COVID-19后,许多患者经历了持续的消化不良症状. 该研究强调,罗马四号标准可能低估了这些功能性胃肠道疾病 (FGID) 的真实患病率.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 感染SARS-CoV-2可能导致胃肠道问题,包括胃肠炎.
- 这些胃肠道问题可以引发各种肠-大脑相互作用 (DGBIs) 或功能性胃肠道障碍 (FGID) 的疾病.
- 在COVID-19之后的后传染性消化不良是一种显著的,但往往被低估的疾病.
研究的目的:
- 为了确定COVID-19住院后消化不良症状的患病率.
- 评估多个时间点的症状持续性:出院后立即,住院后3,6,9个月.
主要方法:
- 这是一项前性单中心研究,涉及320名COVID-19患者.
- 用成人FGIDs的ROME IV诊断问卷的胃肠模块来评估功能性消化不良 (FD).
主要成果:
- 虽然对FD的严格的ROME IV标准的满足率很小 (0-4.8%),但更大的比例 (20.7-23.5%) 报告了暗示FD的GI症状,但不符合时间框架标准.
- 这些暗示性症状在3,6个月和9个月的随访期间持续存在.
结论:
- 持续的胃肠道消化不良症状是COVID-19后的一个重要问题.
- 标准的罗马四标准时间框架可能低估了COVID-19后持续性消化不良症状的患者的实际数量.
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