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在早期发病的高近视症中,冠状腺厚度的模式

Zhaoxin Jiang¹, Aohan Hou¹, Ting Zhang¹

¹State Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Provincial Clinical Research Center for Ocular Diseases, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Frontiers in medicine

|August 4, 2023

概括

儿童的早期高近视 (eoHM) 通常是由简单的高近视 (SHM),斯蒂克勒综合征 (STL) 或家族外性玻璃红斑病变 (FEVR) 引起的. 清晰的冠状腺厚度 (ChT) 模式可以帮助确定eOHM的具体原因.

科学领域:

眼科医生眼科眼科
医疗成像医学成像
遗传学是一个遗传学.

背景情况:

早期高近视 (eoHM) 在儿科眼科护理中是一个重大挑战.
了解潜在的病因及其对眼部结构的影响对于有效的管理至关重要.
胸膜厚度 (ChT) 是眼睛健康和疾病进展的关键指标.

研究的目的:

调查儿童早期高近视 (eoHM) 的病因.
分析与eOHM不同原因相关的冠状腺厚度 (ChT) 模式.
确定潜在的生物标志物,以区分eHM的起源.

主要方法:

研究了一组60名患有eohm的儿童和20名健康对照组.
进行了全面的眼科检查,包括扫描源光学连贯性断层扫描 (SS-OCT).
胸膜厚度 (ChT) 在周围的多个点测量.

主要成果:

简单的高近视 (SHM),斯蒂克勒综合征 (STL) 和家族排泄性视网膜病变 (FEVR) 是最常见的病因.
患有SHM的儿童表现出最薄的CHT鼻腔和劣质 (N2500,I2500).
FEVR与较薄的时间性CHT (T2500) 相关,而STL患者在所有位置都表现出分散的CHT稀释.

结论:

截然不同的ChT模式与eoHM的特定病因有关,包括SHM,STL和FEVR.
不对称的鼻腔ChT稀释可能表明SHM.
不对称的时CHT稀释可能是FEVR的生物标志物,以及STL的扩散稀释,提供一种非侵入性诊断方法.

关键词:

斯蒂克勒综合征 (Stickler Syndrome) 是一种冠状腺厚度冠状腺厚度这是早期发病的早期发病.家庭外表性玻璃红蛋白病变高近视的高近视是一个问题.

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