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Apo 孔隙开放状态作为EAAT离子通道活性增加的功能基础,用于发作性性性衰竭6的病例性衰竭

Mariia Suslova1, Daniel Kortzak1, Jan-Philipp Machtens1

  • 1Institute of Biological Information Processing, Molekular-und Zellphysiologie (IBI-1), Forschungszentrum Jülich, Jülich, Germany.

Frontiers in physiology
|August 4, 2023
PubMed
概括

质谷氨酸转运体 (EAATs) 的突变会损害功能并导致疾病. 这项研究揭示了EAAT4中的特定突变 (P312R) 如何改变离子通道活性,从而提供了对遗传神经系统疾病的见解.

关键词:
阳离子通道的阳离子通道过敏性过敏症 (ataxia) 是一种导致过敏性过敏的疾病.是一种.谷氨酸酸盐的运输方式动态建模运动建模神经系统疾病 神经系统疾病

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