糖尿病外围神经病变 (DPN) 中的运动功能障碍及其测试方式:文献综述
Muhammad Akbar1, Alvian Wandy1, Gita Vita Soraya1,2
1Department of Neurology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Heliyon
|August 4, 2023
概括
糖尿病外围神经病变 (DPN) 影响了许多人,小纤维神经病变 (SFN) 经常在它之前. 通过运动测试进行早期检测对于管理DPN和预防并发症至关重要.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 糖尿病学 糖尿病学
背景情况:
- 糖尿病导致严重的长期并发症,影响多个器官.
- 糖尿病外围神经病变 (DPN) 是一种普遍的并发症,严重影响生活质量并导致残疾.
- 小纤维神经病变 (SFN) 可以先于DPN,并且通常与早期的自主功能障碍有关,特别是运动缺陷.
研究的目的:
- 审查DPN的机制.
- 强调运动评估对早期DPN检测的重要性.
- 分析目前用于SFN诊断的运动测试方法.
主要方法:
- 概述DPN的发病过程.
- 讨论蒸汽机测试原理和应用.
- 对SFN的诊断方式的现有文献的审查.
主要成果:
- 运动功能障碍是DPN中自主神经病变的早期指标.
- 皮肤活检虽然是黄金标准,但对于例行查来说是不切实际的.
- 目前的气动力测试显示了SFN检测的可变灵敏度和特异性.
结论:
- 通过运动评估早期发现SFN对于预防DPN进展和相关心血管事件至关重要.
- 为了有效和常规的DPN诊断,需要在运动测试方面取得进一步的进步.
- 了解运动功能障碍是治疗糖尿病自主神经病变的关键.
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