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针对复发性植入失败的妇女有好处:一种倾向性得分匹配的队列研究

Di Gan^1,2, Li-Ying Liu³, Ying Zhong⁴

¹Chengdu Jinjiang Hospital for Women's and Children's Health, Chengdu, China.

|August 4, 2023

概括

针可以改善复发性植入失败 (RIF) 患者的怀孕率. 虽然它促进了生化和临床怀孕,但它对活产率的影响需要进一步调查.

科学领域:

生殖医学生殖医学
不孕症治疗方法不孕症治疗方法
补充和替代医学补充和替代医学

背景情况:

复发性植入失败 (RIF) 在辅助生殖技术中是一个重大挑战.
确定RIF有效的辅助疗法对于改善患者的治疗结果至关重要.

研究的目的:

评估针作为RIF患者进行冷胚胎移植 (FET) 的辅助疗法的有效性.
评估针对关键生育结果的影响,包括活产率 (LBR),持续妊娠率 (OPR),临床妊娠率 (CPR) 和生化妊娠率 (BPR).

主要方法:

一项回顾性研究,涉及成都西南妇科医院接受FET的923名RIF患者.
患者被分为两组:接受针与激素替代疗法 (HRT) /延迟HRT (d-HRT) 一起治疗的患者和仅接受HRT/d-HRT的对照组.
包括LBR,OPR,CPR,BPR和妊娠损失率在内的结果在各组之间进行了比较.

主要成果:

与非针组相比,针组的生物化学怀孕率 (BPR) (P=0.08) 和临床怀孕率 (CPR) (P=0.049) 显著更高.
在针组中观察到较高的活产率 (LBR) (P=0.16) 和持续妊娠率 (OPR) (P=0.248) 的趋势.
生存率分析没有显示针治疗对活产率的统计学显著改善.

结论:

针似乎是在体外受精 (IVF) 过程中是一种有益的辅助疗法,提高了RIF患者的生化和临床怀孕率.
需要进一步的研究来充分阐明针在整个怀孕周期中的作用和影响.

关键词:

针是一种针疗法.临床怀孕率临床怀孕率在冷胚胎移植过程中,冷胚胎被移植.在试管婴儿受精体外受精.经常发生的植入失败.

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